This study is testing whether a mobile app combined with virtual cognitive behavioral therapy can help people maintain consistent PrEP use while reducing methamphetamine use if they choose to. Researchers hope the study will improve access to supportive tools for sexual health and substance use care.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Ages 18+
• Men who have sex with men
• Had anal intercourse with a man at least once in the past 6 months
• Currently using methamphetamine
• Currently taking daily oral PrEP medication
• HIV-negative
• Own a smartphone
• Live in San Diego, San Francisco Bay Area, or LA
• Willing to participate in a 6-month-long study

If you are eligible and decide to join the study, you will first complete a phone screening interview with the research team.

Participants who enroll will:

• Download and use the CHAMPION study app
• Complete monthly virtual check-ins
• Attend virtual cognitive behavioral therapy sessions
• Provide blood samples every 3 months to measure PrEP usage
• Participate remotely for a total of 6 months
  
  

Participants are randomly assigned to one of two groups:

• An intervention group that receives the CHAMPION program immediately for 6 months
• A waitlist group that begins the program after a 3-month wait period and receives the intervention during the final 3 months of the study

Participants may receive up to $230 for completing all study activities.

Additional perks of participating include:

• Access to virtual cognitive behavioral therapy
• Sexual health and substance use resources
• A fully remote study experience that can be completed from home

There is no cost for you to participate in our research study.