This study is testing whether a mobile app combined with virtual cognitive behavioral therapy can help people maintain consistent PrEP use while reducing methamphetamine use if they choose to. Researchers hope the study will improve access to supportive tools for sexual health and substance use care.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Adult men who have sex with men
• Currently using methamphetamine
• Currently take daily oral PrEP medication
• Ages 18+
• Live in California
• Had anal intercourse with a man at least once in the past 6 months
• HIV-negative
• Own a smartphone
• Willing to participate in a 6-month long study

If you are eligible and decide to join the study, you will first complete a phone screening interview with the research team.

Participants who enroll will:

• Download and use the CHAMPION study app
• Complete monthly virtual check-ins
• Attend virtual cognitive behavioral therapy sessions
• Provide blood samples every 3 months to measure PrEP usage
• Participate remotely for a total of 6 months

Participants are randomly assigned to one of two groups:

• An intervention group that receives the CHAMPION program immediately for 6 months
• A waitlist group that begins the program after a 3-month wait period and receives the intervention during the final 3 months of the study

Participants may receive up to $230 for completing all study activities.

Additional participant benefits include:

• Access to virtual cognitive behavioral therapy
• Sexual health and substance use resources
• A fully remote study experience that can be completed from home

There is no cost for you to participate in our research study.