This study aims to understand how stress from cancer treatment shows up in both biological and digital data. We will look for patterns in wearable data such as heart rate, sleep, and activity that may indicate stress, anxiety, or depression. These digital signals will be compared with saliva samples to see how accurate they are as measures of stress. The goal is to find out if wearable devices can provide a simple, reliable, and non-invasive way to track mental and physical health in people with different types of cancer and treatments.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Women ages 18-59
• In general good health
• Reside in Miami-Dade or Broward County
• No history of cancer
• Willing to wear a wrist-worn wearable device
• Willing to provide weekly saliva samples
• Speak English and be comfortable taking surveys in English

If you are eligible and choose to participate, you will be involved in the study for about a month. There will be two in-person visits for this study.

Visit 1

The first visit, which lasts about one hour, will take place at your home, workplace, or at Florida International University, depending on what is most convenient. During this visit, the research team will:

• Set up the wearable device
• Assist with downloading a survey-taking application
• Provide you with step-by-step training on collecting and storing saliva samples
• Run a brief cognitive test
• Perform some physical measurements of your heart function.

Between Visits

Between visits 1 and 2, you will:

• Wear the device on your wrist continuously for 30 days
• Complete surveys on your phone.
• Collect saliva samples once a week at home

Visit 2

The second visit, which lasts about 10 minutes, will happen at the end of the study at your home. The research team will:

• Collect your wearable device and any remaining materials.

Participants may receive up to $250 for completing all of the study procedures.

There is no cost for you to participate in our research study.