This study is being done to better understand how hormones, menopause-related symptoms, and metabolic factors may affect brain fog in women. The findings may help researchers develop better strategies to support women’s well-being and daily functioning during this stage of life.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Women ages 40-55
• Currently experiencing brain fog
• Able to attend in-person visits at BIDMC
• Perimenopausal

If you qualify and choose to participate, the study will last about 8 weeks and include:

• 1 remote study visit
• 1 visit to a local Quest Diagnostics location
• 3 in-person visits at Beth Israel Deaconess Medical Center in Boston
• At-home saliva collection at various points during the study
• Daily electronic diaries about your symptoms
• Cognitive tasks to assess thinking and memory
• Wearing an activity monitor at various times during the study
• Blood draws and urine collection during in-person visits
• Assessments of mood, fatigue, and diet
• Indirect calorimetry, which measures how your body uses energy

Participants may receive up to $1,000 for completing study activities. The study team can also request a Lyft ride for study-related travel to help with transportation to study visits.

There is no cost for you to participate in our research study.