Recovering from Opioid Use? Join Our Study
Yale University researchers are partnering with individuals who are currently receiving methadone or buprenorphine treatment for a research study aimed at understanding the effectiveness of cannabinoids as an additional treatment option.
VA HSS# 1583127 / 1584988
Yale HIC# 2000027065 / 2000029286
Fast Facts
Currently Receiving Methadone or Buprenorphine
18-70 Years Old
Compensation Provided
Conducted at VA Connecticut Healthcare System, West Haven, CT
Study Background
Could cannabinoids help people treating opioid use disorder?
In 2019, nearly 50,000 people in the United States died from opioid-involved overdoses. The existing treatments for opioid use disorder (OUD) focus on preventing craving and withdrawal symptoms but do not fully address the risk for relapse.
Thus, researchers believe that there is a growing need to develop new treatment options for OUD. This research study explores the short-term effects of cannabinoids among persons with OUD who are receiving treatment with methadone or buprenorphine.
VA Connecticut / Project ID 1583127 / 1584988
Yale HIC # 2000027065 / 2000029286
Study Background
Could cannabinoids help people treating opioid use disorder?
In 2019, nearly 50,000 people in the United States died from opioid-involved overdoses. The existing treatments for opioid use disorder (OUD) focus on preventing craving and withdrawal symptoms but do not fully address the risk for relapse.
Thus, researchers believe that there is a growing need to develop new treatment options for OUD. This research study explores the short-term effects of cannabinoids among persons with OUD who are receiving treatment with methadone or buprenorphine.
VA Connecticut / Project ID 1583127 / 1584988
Yale HIC # 2000027065 / 2000029286
Additional Information
Researchers believe that there is a growing need to develop new treatment options for OUD. This research study explores the short-term effects of cannabinoids among persons with OUD who are receiving treatment with methadone.
You may qualify to participate in this study if you meet the following criteria.
Inclusion Criteria:
- 18-70 years old
- Diagnosed with opioid use disorder (OUD)
- Currently taking buprenorphine (suboxone) or methadone as treatment for opioid use
- Have used cannabis at least once in the past, but currently don’t use it on a daily basis
- Able to attend the research center in New Haven for 4 in-person visits
Exclusion Criteria:
- Bipolar disorder or schizophrenia
- Significant neurological conditions (Alzheimer’s, dementia, stroke)
- Currently pregnant or breastfeeding
- Suicidal ideation
- Sickle cell disease or liver cirrhosis
This is not a treatment study. Although participants may experience temporary effects of the study medication, this is not to be expected to have long-term effects, as they will only receive a single dose on each test day.
Participation will last about 6-8 hours per day for 3-4 test visits.
During the test visits, participants will be asked to take medication containing a different dose each day. The study team can further elaborate on this.
Participants will be asked to complete questionnaires and computer testing.
Participants can be compensated at least $325 for completion of all study procedures. An additional $20 will be compensated for any additional study visits requested.
There is no cost for you to participate in our research study.