Alcohol Use Research Study
Researchers the University of Colorado Anschutz Medical Campus are studying the effect of a medication on alcohol use and brain function.

Fast Facts

Drink 20+ Alcoholic Drinks Per Week

21-65 Years Old

Compensation Provided

Conducted in the Denver Metro area
Study Background
The University of Colorado Translational Addiction Imaging Laboratory (TrAIL) is conducting research studies looking at how medications impact alcohol use and brain function. The medications we are studying, brexpiprazole and tolcapone, are FDA-approved for other treatments but not yet approved for the treatment of alcohol problems or drinking.
Individuals who drink alcohol and who are not seeking treatment to stop or reduce drinking may qualify to join our compensated study!

Study Background

The University of Colorado Translational Addiction Imaging Laboratory (TrAIL) is conducting research studies looking at how medications impact alcohol use and brain function. The medications we are studying, brexpiprazole and tolcapone, are FDA-approved for other treatments but not yet approved for the treatment of alcohol problems or drinking.
Individuals who drink alcohol and who are not seeking treatment to stop or reduce drinking may qualify to join our compensated study!

Additional Information
These research studies plan to learn more about the effect of medications (brexpiprazole and tolcapone) on alcohol use and brain function.
You may qualify for a study if you meet the following criteria.
Inclusion Criteria:
- 21-65 years old
- Consume at least 20 alcoholic drinks per week or consume alcohol frequently
- Not seeking treatment to reduce or stop drinking
- Physically healthy with no history of significant medical illness
- Not currently pregnant or nursing
- Able to undergo an MRI (no non-removable metal on or in your body)
- No history of head injury with loss of consciousness for more than 2 minutes
- Not currently taking psychiatric medications
How much is one drink?
If you join the study, you will have 6 study visits over about 15 days. You will be asked questions, complete questionnaires, give urine and blood samples, have two MRI scans, and take study medication. You will also spend a whole day at the University for a study procedure where you will complete questionnaires and drink some alcohol.
Please note that for study visits where alcohol is consumed, we can arrange a Lyft for transportation to and from the visit.
For participating in the research study you will be paid a total of $650-$700, plus some potential additional payments for other study visit procedures.
There is no cost for you to participate in our research study.