Multiple Sclerosis Research Study
Researchers at Thomas Jefferson University are conducting a study on the physiological effects of an antioxidant in patients with multiple sclerosis.
Fast Facts
Diagnosed with Multiple Sclerosis
Able to Undergo a PET-MRI Scan (no metal in the body)
Compensation Provided
Conducted in the Philadelphia Area
Study Background
Thomas Jefferson University is evaluating whether N-Acetyl Cysteine (NAC) will support cerebral function in patients with multiple sclerosis (MS).
NAC is a derivative of a naturally occurring amino acid and has been shown to reduce fatigue and improve recovery, which has interesting implications for exploring fatigue related to MS.
Participants will undergo a PET-MRI scan of the brain and complete cognitive testing. Participants will receive weekly infusions of NAC for a total of 16 IVs, while taking an NAC capsule twice a day. Brain function and cognition will be assessed pre and post treatment.
Findings from this study will determine if NAC can help improve brain function by reducing inflammation in patients with MS.
Further research and join our compensated study!
Study Background
Thomas Jefferson University is evaluating whether N-Acetyl Cysteine (NAC) will support cerebral function in patients with multiple sclerosis (MS).
NAC is a derivative of a naturally occurring amino acid and has been shown to reduce fatigue and improve recovery, which has interesting implications for exploring fatigue related to MS.
Participants will undergo a PET-MRI scan of the brain and complete cognitive testing. Participants will receive weekly infusions of NAC for a total of 16 IVs, while taking an NAC capsule twice a day. Brain function and cognition will be assessed pre and post treatment.
Findings from this study will determine if NAC can help improve brain function by reducing inflammation in patients with MS.
Further research and join our compensated study!
Additional Information
The purpose of this research study is to determine whether oral/intravenous NAC might help to improve brain function by reducing inflammation in the MS lesions.
You may qualify for this study if you meet the following criteria.
Inclusion Criteria:
- Diagnosed with multiple sclerosis (MS)
- No uncontrolled medical, neurological, or psychiatric conditions
- Able to undergo a PET-MRI scan (no metal in the body)
- PET scan involves injecting a radioactive tracer
- Generally independent
Once enrolled, this study involves:
- Pre-Treatment (3-4 hours):
- Undergoing a PET-MRI scan of the brain in Villanova
- Completing cognitive testing (approximately 20 minutes)
- NAC Treatment (16 weeks):
- Receiving weekly infusions of NAC in Villanova or downtown Philadelphia (approximately 1.5 hours)
- Taking one capsule of NAC twice a day
- Post-Treatment (3-4 hours):
- Undergoing a post PET-MRI scan in Villanova
- Completing follow-up cognitive testing
Compensation is provided up to $100 for your participation.
There is no cost for you to participate in our research study.
