This study is being conducted to better understand whether a form of Vitamin B3 can support brain health and memory in older adults and to explore ways to improve memory and cognitive health.

You may be eligible for this study if you meet the following criteria.

• Ages 60-85
• Identify as a racial minority (Asian, American Indian, Black, Latino, or Pacific Islander)
• Live in the Oklahoma City area
• Have not been diagnosed with dementia or cognitive impairment
• Not currently treated for or have active cancer
• Have not had a stroke within the past 60 days
• Have normal kidney and liver function
• Have not been diagnosed with a central nervous system disease like Parkinson’s disease, Multiple Sclerosis, or a Seizure disorder

Overall Duration

This study lasts about 8 weeks.

In-Lab Activities

Participants will attend study visits at the University of Oklahoma Health Sciences Center. During these visits, they will complete memory and cognitive tests, answer questions about their health, and take part in other study assessments. Participants will also receive the study supplement, which is a form of Vitamin B3, or a placebo (a pill that resembles the supplement bud does not contain any active ingredient) and researchers may collect blood samples to help measure health changes during the study.

Information collected during the study will be kept private. Study data may be recorded and stored securely, but participants’ personal information will be protected.

At-Home Activities

At home, participants will take the study supplement as instructed throughout the 8-week study. They may also be asked to keep track of their supplement use and report any changes in their health or any side effects.

Participants may receive up to $200 in gift cards for their time.

There is no cost for you to participate in our research study.