According to the Centers for Disease Control, over 1 million adults in the United States are diagnosed with type 2 diabetes each year. Over time, high blood sugar from insulin resistance can cause other health conditions like heart problems. Our team is seeking adults with type 2 diabetes, not treated with insulin, to participate in exercise training with a personal trainer 3 times a week at our campus to help us understand if (and how) starting regular exercise can affect blood vessels and heart muscle in people with type 2 diabetes. 

Eventually, this study will help health providers understand how to improve heart health in people with type 2 diabetes.

You may be eligible for this study if you meet the following criteria.

Inclusion Criteria:

• Ages 30-55
• Diagnosed with type 2 diabetes and do not take insulin
• Have been weight-stable for the past three months
• Able to travel to UVA/Charlottesville 3x a week for 15 weeks to complete study visits

Exclusion Criteria:

• Exercise regularly
• Currently taking any GLP-1 or SGLT-2 inhibitor medications
• Are enrolled in another study
• Use tobacco or have used tobacco within the past year
• Have documented cardiovascular disease

Participants will engage in a 15-week exercise program with a personal trainer 3 days/week. There are also 7 total study visits apart from the exercise:

• Screening visit~ 1 hour
• Exercise lab visit (including max ex test and DEXA scan) ~2.5 hours
• Cardiac echo ~1.5 hours
• Outpatient admit (~7 hours, this includes IVs, blood draws, etc.)
• Participants will start 15 weeks of supervised exercise 3 times per week)
• Repeat Exercise lab visit ~2.5 hours 
• Repeat outpatient admit ~7 hours
• Repeat cardiac echo ~1.5 hours

Compensation is provided for study participation.

There is no cost for you to participate in our research study.