Fast Facts
Received a type 1 diabetes diagnosis within the last 6 months
Ages 18-55
Overall in
Good Health
Conducted in
Multiple Locations
Additional Information
The purpose of the POLARIS Study is to evaluate the safety of GNTI-122 and to see whether a single dose of this investigational cell therapy can help preserve remaining insulin-producing cells in adults recently diagnosed with type 1 diabetes.
You may be eligible for this study if you meet the following criteria.
Inclusion Criteria:
- Diagnosed with type 1 diabetes in the last 6 months
- Ages 18-55
- Overall in good health
- Willing to use contraception
Exclusion Criteria:
- Other significant or unstable medical conditions
- Participating in another interventional clinical study
- Pregnant or breastfeeding
The POLARIS Study is a multi-center clinical trial being conducted at leading research institutions across the United States, including:
- City of Hope Medical Center – Duarte, CA
- University of California, San Diego – San Diego, CA
- University of California, San Francisco – San Francisco, CA
- University of Florida – Gainesville, FL
- University of Miami, Diabetes Research Institute – Miami, FL
- Joslin Diabetes Center – Boston, MA
- University of North Carolina at Chapel Hill – Chapel Hill, NC
- Duke University –Durham, NC
- Columbia University – New York, NY
- Icahn School of Medicine at Mount Sinai – New York, NY
Additional locations may be added over time.
If you choose to participate, your involvement may include:
A phone screening to determine initial eligibility
An in-person screening visit, including medical history and lab tests
Collection of white blood cells through a procedure called leukapheresis
A one-time administration of the investigational therapy (GNTI-122)
Follow-up visits at the study site to monitor safety, immune response, and diabetes progression
All study procedures are explained in detail before participation, and you may leave the study at any time.
Participants will receive compensation for time and travel, which varies by study site and follows industry standards for studies of similar complexity. Parking assistance or transportation support may also be available.
There is no cost for you to participate in our research study.