Brain Imaging Research Study

Research study involving state-of-the-art brain imaging at Stony Brook University Medical Center

Fast Facts

Aged 18–65 With Chronic Depression

Free Outpatient Treatment

Compensation

Provided

Conducted in

Stony Brook, NY

About this research study:

Treating depression using an FDA-approved* anti-inflammatory (nonsteroidal anti- inflammatory drug, NSAID)

The Department of Psychiatry at Stony Brook University is one of the region’s premier providers of psychiatric services and a national leader in neuroimaging research. The study involves Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) imaging of the brain. PET and MRI brain imaging is performed before and after 8 weeks of NSAID treatment. This medication is FDA approved as an anti-inflammatory and may be effective to treat depression, especially if other treatments have failed. Your participation in this research study may help further our understanding of depression and other psychiatric illnesses.

*Please note: This medication is currently FDA approved as an anti-inflammatory, not as an antidepressant medication.

Study Background

Treating depression using an FDA-approved* anti-inflammatory (nonsteroidal anti- inflammatory drug, NSAID)

The Department of Psychiatry at Stony Brook University is one of the region’s premier providers of psychiatric services and a national leader in neuroimaging research. The study involves Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) imaging of the brain. PET and MRI brain imaging is performed before and after 8 weeks of NSAID treatment. This medication is FDA approved as an anti-inflammatory and may be effective to treat depression, especially if other treatments have failed. Your participation in this research study may help further our understanding of depression and other psychiatric illnesses.

*Please note: This medication is currently FDA approved as an anti-inflammatory, not as an antidepressant medication.

Additional Information

According to the World Health Organization, depression will be the 2 nd leading cause of
disability this year. Depression is a common, painful and disabling disorder. Your participation in this research study may help further our understanding of depression and other psychiatric illnesses.

Adults between 18 and 65 years old who are currently depressed are eligible.

The study provides 8 weeks of free outpatient treatment with a medication that reduces inflammation (nonsteroidal anti-inflammatory drug, NSAID). Brain imaging will be performed before and after treatment to learn more about the relationship between depression and inflammation.
 

The study involves Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) imaging of the brain. PET and MRI brain imaging is performed before and after 8 weeks of NSAID treatment. This medication is FDA approved as an anti-inflammatory and may be effective to treat depression, especially if other treatments have failed. During treatment, you will be provided with free clinical appointments. Throughout the study, you will be interviewed about your physical and emotional health.

You will be given up to $480 for completing the study.

You will receive free outpatient medication and a comprehensive medical and psychological evaluation during the study.

There is no cost for you to participate in our research study.