Brain Imaging Research Study
Research study involving state-of-the-art brain imaging at Stony Brook University Medical Center
Fast Facts
Aged 18–65 With Chronic Depression
Free Outpatient Treatment
Compensation
Provided
Conducted in
Stony Brook, NY
Study Background
Researchers at the University of Pittsburgh are conducting studies in adolescents and young adults to understand depression, how it develops, and how to change it.
Depression and a symptom called anhedonia, which involves difficulty with motivation, energy, and anticipation of pleasant events, are related to disruptions in positive emotions and could be based on alterations in the brain’s dopamine system and reward circuitry. We aim to learn more about alternative treatments for people whose depression does not improve with traditional treatments. We also want to understand depression early in life so that we can find ways to help young people develop along healthy pathways and avoid chronic illness.
Eventually, the findings of this study might be useful for treating depression and improving people’s quality of life.
Study Background
Researchers at the University of Pittsburgh are conducting studies in adolescents and young adults to understand depression, how it develops, and how to change it.
Depression and a symptom called anhedonia, which involves difficulty with motivation, energy, and anticipation of pleasant events, are related to disruptions in positive emotions and could be based on alterations in the brain’s dopamine system and reward circuitry. We aim to learn more about alternative treatments for people whose depression does not improve with traditional treatments. We also want to understand depression early in life so that we can find ways to help young people develop along healthy pathways and avoid chronic illness.
Eventually, the findings of this study might be useful for treating depression and improving people’s quality of life.
Additional Information
According to the World Health Organization, depression will be the 2 nd leading cause of
disability this year. Depression is a common, painful and disabling disorder. Your participation in this research study may help further our understanding of depression and other psychiatric illnesses.
Adults between 18 and 65 years old who are currently depressed are eligible.
The study involves Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) imaging of the brain. PET and MRI brain imaging is performed before and after 8 weeks of NSAID treatment. This medication is FDA approved as an anti-inflammatory and may be effective to treat depression, especially if other treatments have failed. During treatment, you will be provided with free clinical appointments. Throughout the study, you will be interviewed about your physical and emotional health.
You will be given up to $480 for completing the study.
You will receive free outpatient medication and a comprehensive medical and psychological evaluation during the study.
There is no cost for you to participate in our research study.