Opioid Dependency Research Study
Researchers at the University of Pennsylvania are conducting a study to learn more about how an outpatient treatment might help opioid withdrawal symptoms for adults with opioid dependency struggling to reduce or stop opioid use.
Fast Facts
Adults Struggling With Opioid Dependency & Looking to Reduce or Stop Use
Not Currently
in a Treatment Program
Compensation
Provided
Conducted in
Philadelphia, PA
(with some remote visits)
Study Background
Join a research study aimed at helping adults dependent on opioids cut down safely.
This study is designed for adults in the Philadelphia area who are struggling with opioid dependency and not currently enrolled in another treatment program.
After the screening process, participants will receive outpatient medications for 10 days to help manage withdrawal symptoms while working toward reducing opioid use. The treatment protocol being used in this research study showed benefits when used in an inpatient setting, and researchers hypothesize a similar benefit in this outpatient study.
Participation includes both in-person and telemedicine visits, providing flexibility for your schedule.
Further research on opioid withdrawal treatments and join our compensated study!
Study Background
Join a research study aimed at helping adults dependent on opioids cut down safely.
This study is designed for adults in the Philadelphia area who are struggling with opioid dependency and not currently enrolled in another treatment program. Participants will receive outpatient medications, including lofexidine and pregabalin, to help manage withdrawal symptoms while working toward reducing opioid use.
The research will also explore the transition to Vivitrol, a long-acting injectable treatment for opioid dependency, and measure outcomes using standard withdrawal scales. Participation includes both in-person and telemedicine visits, providing flexibility for your schedule.
Additional Information
This study is being conducted to evaluate long-acting outpatient treatment options that help adults safely manage opioid withdrawal symptoms like achiness, anxiety, insomnia, and more.
You may be eligible for this study if you meet the following criteria.
Inclusion Criteria:
- Ages 18+
- Struggling with opioid dependency and looking to reduce or stop use
Exclusion Criteria:
- Currently in a treatment program
- Significant medical conditions
- Taking psychoactive medications (antidepressants, mood stabilizers, stimulants)
- Other substance use disorders
After the screening process, participants will take the medications as an outpatient for about 10 days. Study visits occur over approximately 6 to 7 days. Some of these visits may take place through telemedicine.
Contact Information:
The Treatment Research Center
University of Pennsylvania
3535 Market Street, suite 500
Philadelphia, PA 19104
215-746-0467
There is no cost for you to participate in our research study.