High Blood Pressure Clinical Trial
Researchers at Trialmed are conducting a clinical trial on a medication for adults with high blood pressure and cardiovascular disease or high cardiovascular risk.
Fast Facts
High Blood Pressure That Is Not Well Controlled
Taking At Least 2 Blood Pressure Medications, Including A Diuretic (Water Pill)
If Eligible, You Will be Reimbursed for Study-Related Time and Travel
Conducted In the UK
Trial Background
This trial is evaluating a potential treatment for adults whose high blood pressure is not well controlled.
The research is testing an investigational medication given as an injection under the skin every six months, in addition to participants’ current blood pressure medications. The goal is to determine whether this medication can help reduce the risk of serious cardiovascular events such as heart attack, stroke, heart failure, or cardiovascular death.
This trial may be especially relevant for people with a history of cardiovascular disease, including conditions affecting the heart, brain, or circulation.
Trial Background
This trial is evaluating a new treatment for adults whose high blood pressure is not well controlled.
The research is testing an investigational medication given as an injection under the skin every six months, in addition to participants’ current blood pressure medications. The goal is to determine whether this medication can help reduce the risk of serious cardiovascular events such as heart attack, stroke, heart failure, or cardiovascular death.
This trial may be especially relevant for people with a history of cardiovascular disease, including conditions affecting the heart, brain, or circulation.
Additional Information
Researchers want to see if a medication to standard blood pressure treatment can lower the risk of major cardiovascular events while improving overall heart and kidney health.
This trial may be especially relevant for individuals with a history of cardiovascular disease (such as heart disease, stroke, or poor circulation). You may be eligible for this study if you meet the following criteria.
Inclusion Criteria:
- High blood pressure that is not well controlled
- Taking at least 2 blood pressure medications, including a diuretic (water pill)
- Not pregnant
- History of heart or blood vessel problems, or considered at high risk for heart disease (e.g., at least 70 or older, diagnosed with diabetes, overweight, smoke cigarettes)
- Not participating in another clinical trial
- No cancer in the past 5 years
Screening: A telephone interview to confirm eligibility.
Study Visits: Approximately 10–14 in-person visits over 2.5–5 years at one of the UK sites.
Medication: An injection under the skin every six months (study drug or placebo).
Monitoring: Participants continue their usual blood pressure medications and receive regular health evaluations, laboratory tests, and cardiovascular monitoring.
3 UK Site locations:
Glasgow, Birmingham/Midlands, Cardiff
There is no cost for you to participate in our clinical trial. If eligible, participants will be reimbursed for study-related time and travel.